Volume 5, number 1
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Protection by the Fenugreek seeds alkaloid against mitotic crossing over, gene conversion and reverse mutation included by tegretol in Saccharomyces cerevisiae D7

Nada, H. A. Al-Twaty

Department of Biology, Faculty of Science, King Abdulaziz University, P .O. Box 42613- Jeddah 215 51 Saudi Arabia.

ABSTRACT: Protection by the fenugreek seeds alkaloid against mitotic crossing over, gene conversion and reverse mutation included by tegretol were investigated in Saccharomyces cerevisiae D7. Also estimate the alteration of protein banding after individual and combined treatments by using protein electrophoresis analysis. The single treatment of tegretol due significant reduction on survival percentage and induced mitotic crossing over , gene conversion and reverse mutation. The previous treatments with fenugreek with tegretol reduse all studied genetic mutation frequency than tegretol alone. All the combined treatments with fenugreek and tegretol did not affect in general on the density of protein bands , in comparison with tegretol separately.

KEYWORDS: Saccharomyces cerevisiae D7; Genotoxicity; Antimutagenicity; fenugreek seeds-tegretol

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Nada, Al-Twaty H. A. Protection by the Fenugreek seeds alkaloid against mitotic crossing over, gene conversion and reverse mutation included by tegretol in Saccharomyces cerevisiae D7. Biosci Biotechnol Res Asia 2008;5(1)
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Nada, Al-Twaty H. A. Protection by the Fenugreek seeds alkaloid against mitotic crossing over, gene conversion and reverse mutation included by tegretol in Saccharomyces cerevisiae D7. Biosci Biotechnol Res Asia 2008;5(1). Available from: https://www.biotech-asia.org/?p=6434

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