Volume 5, number 1
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Spectrophotometric Method For the Determination of Gemifloxacin Mesylate in Bulk and Pharmaceutical Formulations

M.Sugumaran* V. Meganathan and T. Vetrichelvan

Adhiparasakthi College of pharmacy, Melmaruvthur - 603 319 India.

Corresponding Author E-mail: murugesansugumaran@yahoo.com

ABSTRACT: A simple, sensitive and reproducible spectrophotometric method was developed for the determination of Gemifloxacin mesylate in bulk and its pharmaceutical formulations. This method was based on the reaction of Gemifloxacin mesylate with Fe(III) of ferric nitrate and 0.1M hydrochloric acid to produce a orange colored chromogen (lmax at 471nm). Results of analysis were validated statistically and by recovery studies. This method was successfully employed for the determination of Gemifloxacin mesylate in various pharmaceutical preparations.

KEYWORDS: Gemifloxacin mesylate; Visible spectrophotometric determination; Beer’s Law

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Sugumaran M, Meganathan V, Vetrichelvan T. Spectrophotometric Method For the Determination of Gemifloxacin Mesylate in Bulk and Pharmaceutical Formulations. Biosci Biotechnol Res Asia 2008;5(1)
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Sugumaran M, Meganathan V, Vetrichelvan T. Spectrophotometric Method For the Determination of Gemifloxacin Mesylate in Bulk and Pharmaceutical Formulations. Biosci Biotechnol Res Asia 2008;5(1) Available from: https://www.biotech-asia.org/?p=7092

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