Volume 5, number 2
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Anti-ulcer activity of alcoholic leaf extract of Pithecellobium dulce Benth

M. Sugumaran, T. Vetrichelvan And S.Darlin Quine

1Adhiparasakthi College of Pharmacy, Melmaruvathur - 603 319 India. 2School of Chemical and Biotechnology, SASTRA University, Thanjavur - 613 402 India.   Corresponding Author E-mail: murugesansugumaran@yahoo.com

ABSTRACT: Ethanolic leaf extract of Pithecellobium dulce was studied for its anti ulcer activity in pyloric ligated ulcer model in rats. The volume of gastric juice, pH , and ulcer index were reduced significantly (P< 0.001 ) in the animals pretreated with alcoholic extract at the tested dose level. HPTLC fingerprint profile of the same extract was developed which would serve as reference standard for quality control of this extract.

KEYWORDS:

Pithecellobium dulce; antiulcer activity; Pyloric-ligated ulcer model

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M. Sugumaran, T. Vetrichelvan And S.Darlin Quine. Anti-ulcer activity of alcoholic leaf extract of Pithecellobium dulce Benth. Biosci Biotechnol Res Asia 2008;5(2).

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M. Sugumaran, T. Vetrichelvan And S.Darlin Quine. Anti-ulcer activity of alcoholic leaf extract of Pithecellobium dulce Benth. Biosci Biotechnol Res Asia 2008;5(2).Available from:

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