Non-High Density Lipoprotein Cholesterol, Lipid Ratios and Risk of Cardiovascular Diseases

Sampath Kumar¹ and A. Vijaya Anand²

¹Department of Biochemistry, SASTRA University, SRC, Kumbakonam India.

²Department of Biochemistry, M.I.E.T. Arts and Science College, Tiruchirappalli India.

Corresponding Author E-mail: avamiet@yahoo.com

ABSTRACT: Cardiovascular disease (CVD) is multifactorial in etiology. No other life–threatening disease is as prevalent or expensive to society as CVD. Hence it is essential to diagnose the complications with multi markers and inexpensive methods. Atherogenic dyslipidemia, metabolic syndrome, non-high-density lipoprotein (non–HDL) cholesterol and lipid ratio offers the benefit of being an aggregate measure and currently believed to contribute to atherosclerosis. Therefore the present study was aimed to investigate the role atherogenic dyslipidemia, metabolic syndrome, non–HDL cholesterol and the various lipid ratios as an individual marker of cardiovascular events. Two hundred patients were recruited for the study, of which hundred belongs to control and hundred were had CVD (test group). The result showed that the test group have elevated levels of total cholesterol (TC), triglyceride (TG), low-density lipoprotein (LDL) cholesterol, non-HDL cholesterol and various lipid ratios promotes CVD. Similarly, decreased levels of high-density lipoprotein (HDL) cholesterol were associated with the development of CVD. Atherogenic dyslipidemia and metabolic syndrome were also positively associated with CVD. These are more sophisticated methodology than that used in routine clinical practice can identify these multiple interrelated abnormalities.

KEYWORDS: Atherogenic dyslipidemia; Metabolic syndrome; Non-HDL cholesterol; Lipid ratio

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