The Study on the Prevalence of Hypercalciuria and Hypercalcemia in patients with Urinary stones

Banafshe Dormanesh¹, Hamid Reza Safaei¹ and Hamid Pirasteh^2*

¹Department of Pediatric Nephrology, AJA University of Medical Sciences, Tehran, Iran. ²Department of Nephrology, AJA University of Medical Sciences, Tehran, Iran.

DOI : http://dx.doi.org/10.13005/bbra/1618

ABSTRACT: Urinary stones are one of the common diseases of urinary system. They can impose many clinical problems and complications, as pain, hematuria, urinary tract obstruction, infection, renal failure and hypertention. It is important to study the prevalence of the main metabolic disorders found in patients with diagnosis of urolithiasis in our Country. Appropriate management of these disorders can diminish the recurrence rate of urinary stone. We made a retrospective study on 193 patients with history of the urinary stone that referred to nephrology clinic and surveyed for metabolic disorders. Metabolic study consisted of blood calcium and creatinine levels, in addition to the volume of 24-hour urine creatinine and calcium. The blood parathormone level test was performed in patients suspected to hyperparathyroidism The number of men with urinary stone was 131 and the number of women was 62, the prevalence of disease in men was 2.1 fold than women. In our study the prevalence of hypercalciuria was different from studies in developed countries, where hypercalciuria is the most common disorder. The differences may be due to genetic and racial differences or different nutritional habits or environmental factors. We suggest more studies on genetic and racial factors and nutritional habits.

KEYWORDS: Urinary stones; Metabolic disorder; Hypercalciuria ; Hypercalcemia

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