Vol12(spl.Edn.1)
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Distribution of SCCmec types in Staphylococcus aureus Strains Isolated from the Pediatrics Suffered From Severe UTIs

Hamid Reza Safaei1, Hamid Pirasteh2, Zahra Pournasiri3 and Banafshe Dormanesh1

1Department of Pediatric Nephrology, AJA University of Medical Sciences, Tehran, Iran. 2Department of Nephrology, AJA University of Medical Sciences, Tehran, Iran. 3Department of Pediatric Nephrology , Shahid Beheshti University of Medical Sciences, Tehran, Iran.

DOI : http://dx.doi.org/10.13005/bbra/1619

ABSTRACT: Staphylococcal cassette chromosome mec (SCCmec) is a mobile genetic element of Staphylococcus aureus which includes the mecA gene coding for resistance to the methicillin and other types of -lactam antibiotics. The present study was carried out to investigate the distribution of SCCmec types in S. aureus strains isolated from the urine samples of pediatrics suffered from UTIs. Totally, 162 urine samples were collected from hospitalized pediatrics suffered from UTIs. Samples were cultured and those that were S. aureus-positive were analyzed for the presence of SCCmec types I, II, III, IVa, IVb, IVc, IVd and V. Of 162 studied samples, 56 samples (34.56%) were S. aureus positive. Total prevalence of S. aureus in boy and girl patients were 29.16% and 38.88%, respectively (P= 0.048). the prevalence of S. aureus in the cases of pyelonephritis and cystitis were 38.82% and 29.87%, respectively (P= 0.045). Total prevalence of SCCmec types I, II, III, Iva, IVb, IVc, IVd and V in the S. aureus isolates were 26.78%, 17.85%, 35.71%, 19.64%, 30.35%, 14.28%, 10.71% and 46.42%, respectively. Higher prevalence of SCCmec types was reported in the cases of pyelonephritis and also in girl patients. As far as we know, the present study was the first prevalence report of SCCmec types of S. aureus isolated from Iranian pediatric patients. Our data showed that researchers should tried to find a proper replacement for methicillin.

KEYWORDS: Staphylococcus aureus; SCCmec types; Urinary tract infections; Pediatrics; Iran

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Safaei H. R, Pirasteh H, Pournasiri Z, Dormanesh B. Distribution of SCCmec types in Staphylococcus aureus Strains Isolated from the Pediatrics Suffered From Severe UTIs. Biosci Biotech Res Asia 2015;12(spl.edn.1)
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Safaei H. R, Pirasteh H, Pournasiri Z, Dormanesh B. Distribution of SCCmec types in Staphylococcus aureus Strains Isolated from the Pediatrics Suffered From Severe UTIs. Biosci Biotech Res Asia 2015;12(spl.edn.1). Available from:https://www.biotech-asia.org/?p=12712

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