Isolation, Purification and Application of Secondary Metabolites from Lichen Parmelia Perlata

Leela K and Anchana Devi C.

PG and Research Department of Biotechnology, Women’s Christian college, College road, Chennai - 600006, Tamilnadu, India.

Corresponding Author E-mail: dr.anchanababu@gmail.com

DOI : http://dx.doi.org/10.13005/bbra/2587

ABSTRACT: Lichens are composite algae having a symbiotic association with a fungal partner. They produce numerous secondary metabolites, which play an important role in pharmaceutical and in other industrial applications. The Secondary metabolites produced by lichens are found to be 80% more when compared to that produced by other organisms. Not much work has been carried out on lichens due to the difficulty in their cultivation but still it emerges as a potential source in developing therapeutically important drugs which are widely beneficial in all fields of application. The Present study was aimed to isolate, purify and determine the applications of secondary metabolites from Lichen Parmelia perlata. The presence of these compounds were detected and purified by thin layer chromatography and column chromatography using specific solvent systems. The purified fractions were then identified by Gas chromatography-Mass spectrometry (GC-MS). The compounds were then subjected to application oriented studies such as antimicrobial activity, antioxidant activity and antidiabetic activity. Not much work have been carried out on the isolation of a specific glycoside and alkaloid compound from Lichen Parmelia perlata, so this study was an attempt to explore the applications of these individual compounds which could prove beneficial to the mankind for different purposes.

KEYWORDS: Column Chromatography; Gas Chromatography-Mass Spectrometry Parmelia Perlata; Secondary Metabolites; Thin Layer Chromatography;

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