Role of Green Route Synthesized Silver Nanoparticles in Medicinal Applications with Special Reference to Cancer Therapy

S. Rizwana Begum¹, D. Muralidhara Rao² and P. Dinesh Sankar Reddy¹

¹Jawaharlal Nehru Technological University, Ananthapuramu- 515002, AP, India.

²Sri KrishnaDevaraya University, Ananthapuramu- 515003, AP, India.

Corrsponding Author E-mail: pdsreddy@gmail.com

DOI : http://dx.doi.org/10.13005/bbra/2686

ABSTRACT: Nanotechnology is a blazing field for the researchers in modern branch of science along with engineering have lot of applications. Nanotechnology is an imminent field with new outlet to fight and prevent many diseases using nanoparticles. Among the most promising materials Silver nanoparticles are having antimicrobial properties which are synthesized from medicinal plant and acts against chronic diseases. Silver nanoparticles synthesized from medicinal plants have lot of applications and eco-friendly, cost effective in nature. The present review article mainly focuses on biologically synthesized silver nanoparticles from medicinal plants and its role on cancer cells. Cancer is one of the most difficult health issues on globe. Although number of treatments may include radiation, chemotherapy and surgery, but these procedures not only targets tumor tissue but also normal healthy tissue. In recent years silver nanoparticles are considered as promising tool for cancer therapy. A numerous studies both in-vitro and in-vivo suggested that sliver nanoparticles can be used as cytotoxic and genotoxic agent due to their apoptotic inducing and anti-proliferative properties. However there is need to overlook the mechanism regarding the anti-cancerous activity. A silver nanoparticle deploys in every field of engineering science and medical sciences are still attracting to explore new scope of nanobiotechnology attributed with smaller size particles.

KEYWORDS: Cancer; Green Synthesis; Nanotechnology; Medicinal Plants; Sliver Nanoparticles

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