Bacteriospermia – An Important Factor Which Needs More Attention in Infertility Care

Mathan Periasamy¹, M. Elanchezhian^2* and Surulimuthu Muthiah³

¹Department of Microbiology, Ponnaiyah Ramajayam Institute of Science and Technology, Thanjavur, India– 613403.

²Komali Fertility Centre, A unit of Ramesh Cardiac and Multispeciality Hospitals, Guntur, India-522004.

³Institute of Bio-Medical Research, Chennai, India – 600017.

Corresponding Author Email: avarnan.che@gmail.com

DOI : http://dx.doi.org/10.13005/bbra/2832

ABSTRACT: Infertility is one of the increasing problems in the global scenario that affects a large number of human couples. The fertilizing potential of semen or seminal parameters such as sperm concentration, motility, morphology, etc., is declining in healthy men which need to be approached in a broad manner in terms of diagnosis and treatments. Genitourinary tract infections by microorganisms are one of the causes of male infertility and particularly bacteriospermia, the inflammation by bacterial pathogens play a major role that result in abnormal seminal parameters. Apart from their influence on seminal parameters, bacteriospermia is also associated with DNA fragmentation in sperms and production of reactive oxygen intermediates in semen. This review discusses on the influence of various bacteria that affect the seminal parameters and thereby cause male infertility. It has become a necessity to consider bacteriospermia as an influential factor affecting male fertility and hence, screening for bacterial infection should be essentially carried out before treatment to overcome the infertility.

KEYWORDS: Bacteriospermia; DNA Fragmentation; Infertility; IVF; ROI; Seminal Parameters

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