Study Of Phorate Toxicity By Analysis Of Electrolytes And Urea In Serum Of Albino Rats

Mustaq Ali and Rani Pillai

Department of Biochemistry, Government Shakir Ali Khan Hospital (G.R.) Bhopal - 462 001 (India)

ABSTRACT: Oral administration of freshly prepared doses of Phorate (O,O, diethyl S-ethyl thio methyl phosphorodithioate) was sprayed. Which were then fed to albino-rats once in a day and five times in a week for a period of 21 days administration of phorate sprayed soybean showed biochemical changes in serum of albino rats. The value of blood urea were decreased from 35.5 to 29.8 mg/dl and significant change in Na+ and K+ level found to be 157.8m Eq/L and 6.81 m Eg/L respectively.

KEYWORDS: Phorate toxicity; electrolytes; urea; serum; albino rats

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