Identification and Assessment of Non-Genetic Factors Contributing to Nephrolithiasis (Kidney Stone) in the Jammu Region

Kanak Mahajan¹ , Meenakshi Bhagat² , Jessica Cherukuri¹ , Rahul Gupta³, Amrit Sudershan^1,4, Rakesh Kumar Panjaliya¹ and Parvinder Kumar^1,2

¹Institute of Human Genetics, University of Jammu, J and K, India.

²Department of Zoology, University of Jammu, J and K, India.

³Department of Urology, Govt. Super Specialty Hospital, Jammu, India.

⁴Department of Human Genetics, Sri Pratap College, Cluster University of Srinagar, Kashmir, J and K, India

Corresponding Author E-mail: parvinderkb2003@gmail.com

DOI : http://dx.doi.org/10.13005/bbra/3140

ABSTRACT: The current study sought to identify and quantify the prevalence of various risk factors for nephrolithiasis in the population of Jammu region. In the present study, a total of 100 study participants (50 cases and 50 controls) were enrolled. A detailed health questionnaire covering different risk factors viz., socio-demographic, biochemical, clinical and lifestyle parameters were designed for the study. The results revealed a significant association between physical inactivity and risk of nephrolithiasis. On comparison of biochemical parameters between the male and female patients, it was observed that overall male patients have slightly higher mean values of biochemical factors. Water being an important factor for reducing the risk of kidney stone but the consumption of water is also low (less than 3 liters/day) in most of the patients.

KEYWORDS: Cases; Controls; Nephrolithiasis; Socio-Demographic Parameters; Statistical Analysis

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