A Short Review - Biochemical Aspects and Advancements in Gastric Cancer

Rajeev Ramachandra Kolgi¹ , Bhargavi G², Nataraju Angaswamy² , M V. Srinivasulu³ and S. Shankara Somashetty^4*

¹Department of Chemistry and Biochemistry, Government Science College, Bengaluru, Karnataka , India.

²Department of Biochemistry, Karnataka State Open University, Mysuru-06. Karnataka, India.

³Department of Botany, Government Science College, Bengaluru-01. Karnataka, India

⁴Department of Microbiology, Government Science College, Bengaluru-01. Karnataka, India.

Corresponding Author E-mal: drshankarmicro@gmail.com

DOI : http://dx.doi.org/10.13005/bbra/3203

ABSTRACT: Malignancy in the stomach is one of the silent causes of mortality due to a bad prognosis regardless of gender. It is the world's Fourth leading cause of death It is a disorder in which cancerous cells form in the stomach lining. The primary relationships begin between its carcinogenic route and Helicobacter pylori infection, following inflammation, and tissue regeneration. The review aims to evaluate biochemistry related to gastric cancer which focuses on cancer research including etiology, molecular basis, malignant transformation, tumor markers, prognosis, advancements in gastric (stomach) cancer and its therapeutics. The study of prognosis and advancements in gastric cancer helps a researcher, medical practitioner, or surgeon to develop safe, minimally invasive, and effective methods to prevent, screen, diagnose, and treat gastric cancer.

KEYWORDS: Adenocarcinoma; Chemotherapy; Etiology; Gastric Cancer; Helicobacter Pylori; Tumor Markers

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