Assessment of Intradialytic Complications and Predisposing Factors in Chronic Kidney Disease Individuals Receiving Hemodialysis

Lokesh Narayanaswamy^1*, Rakshitha Gonur Prakasha Murthy¹, Nataraj Gowda Rajappa² , Aravind Patil ³ , Aman Suresh Tharayil⁴ and Vaishnavi Sairaman⁵

¹Department of Pharmacy Practice, S.J.M. College of Pharmacy, Chitradurga, Karnataka, India

²Department of Pharmacology, S.J.M. College of Pharmacy, Chitradurga, Karnataka, India

³Department of Nephrology, BMCH and RC Hospital, Chitradurga, Karnataka, India

⁴Department of Pharmacy Practice Sandip institute of pharmaceutical sciences, Nashik, Maharashtra, India

⁵Department of Pharmacy Practice, Arulmigu kalasalingam college of pharmacy, Krishnan Koil, Tamil Nadu, India.

Corresponding Author E-mail:lokisaho789@gmail.com

DOI : http://dx.doi.org/10.13005/bbra/3336

ABSTRACT: The investigation focused on assessing the prevalence of complications and predisposing factors, assessing the co-morbidities, and comparing the risk of age and complications as hypertension in CKD patients undergoing haemodialysis. A prospective observational investigation was undertaken across two separate sites. Basaveshwara Medical College & Hospital and Akshaya Global Hospital, Chitradurga. The data was collected in a pre-designed data collection form after obtaining the patient's consent. After the data collection, the information was entered into an Excel spreadsheet and subjected to analysis. The statistical analysis includes the calculation of percentages, the generation of descriptive statistics, and the computation of Pearson correlations. The study enrolled 70 patients; there were more multiple complications and predisposing factors compared to single complications and predisposing factors. The prevalence of complications such as muscle cramps (75.75%), followed by chills (47.10%), itching (38.50%), and hypotension (34.30%), were in higher. While predisposing factors such as elevated blood pressure (88.6%) and diabetes mellitus (65.7%) were more commonly observed. Co-morbid conditions of hypertension and diabetes (47.15%) were found more. Insignificant correlation was found between age as a risk factor and hypertension as a complication. Our study concludes that muscle cramps, chills, itching, and hypotension were common complications, while hypertension and diabetes were frequent predisposing factors. Hypertension with diabetes was the most common comorbidity, and no significant age-related correlation with hypertension as a complication was observed.

KEYWORDS:

Chronic Kidney Disease; Co-morbidities; Complications; Hemodialysis; Risk Factors

[ HTML Full Text]