Volume 4, number 2
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Antidiabetic activity of stem extracts of Tinospora cordifolia on streptozotocin induced diabetic Wistar rat

Mohammed Abdullah, Y. Al Eryani and Prakash R. Naik*

Endocrinology Laboratory, Department of Zoology, University of Mysore, Mysore - 570 006 (India)

ABSTRACT: The aim of the present experiment was to evaluate therapeutic efficacy of stem extracts of Tinospora cordifolia on diabetes induced animal model Wistar rat. Experimental animals were grouped in to control (I), control with T. cordifolia stem extract (II) control diabetic (III) and Diabetic group with T. cordifolia stem extract treated with 100 mg/kg body weight for 35 day (IV). Blood glucose, glycosylated haemoglobin, triglycerides, cholesterol, LDL, VLDL, HDL and blood urea were measured at the beginning and termination of experiments. Blood glucose and other parameters were elevated in diabetic group. Elevated levels were significantly reduced in alleviating the diabetic condition after treatment with stem extract of T. cordifolia.

KEYWORDS: Diabetic rat; Tinospora cordifolia; Glycosylated haemoglobin; Cholesterol; HDL; LDL; VLDL

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Abdullah M, Eryani Y. A, Naik P. R, Antidiabetic activity of stem extracts of Tinospora cordifolia on streptozotocin induced diabetic Wistar rat. Biosci Biotechnol Res Asia 2007;4(2)
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Abdullah M, Eryani Y. A, Naik P. R, Antidiabetic activity of stem extracts of Tinospora cordifolia on streptozotocin induced diabetic Wistar rat. Biosci Biotechnol Res Asia 2007;4(2). Available from: https://www.biotech-asia.org/?p=6003

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