Volume 6, number 1
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Production of Galacto-Oligosaccharides by Marine Derived Fungus Aspergillus Flavus

A. Pavani, T. Prabhakar and G. Girija sankar

A. U. College of Pharmaceutical Sciences, Andhra University, Visakhapatnam - 530 003 India.

Corresponding Author E-mail: pavani71@gmail.com

ABSTRACT: The aim of this research is to develop a cost effective method for the synthesis of oligosaccharides by using Aspergillus flavus (MTTC 9349) screened from marine fungus. This study was carried out, with a view of the marine strains may have better potential than their terrestrial counterparts. This is due to essential nutrients provided by marine biotopes for nurturing the isolates, and to extreme environmental niches. The marine fungi and their by-products may have potential values in food processing, fermentation, pharmaceutical and biopolymer industries. In this project we developed a production process of galacto-oligosaccharides (GOS), also known as Bifidus growth factor, are produced from lactose. The synthesis of GOS carried out by permeabilized and mutated cells of A. flavus. The process was optimized with different chemical agents for permeabilization; at substrate (lactose) concentrations ranging from 0.5 M to 2.25 M and pH.

KEYWORDS: A. flavus; Marine derived fungus; b-galactosidase; GOS. Bifidus factor

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Pavani A, Prabhakar T, sankar G. G. Production of Galacto-Oligosaccharides by Marine Derived Fungus Aspergillus Flavus. Biosci Biotechnol Res Asia 2008;6(1)
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Pavani A, Prabhakar T, sankar G. G. Production of Galacto-Oligosaccharides by Marine Derived Fungus Aspergillus Flavus. Biosci Biotechnol Res Asia 2008;6(1) . Available from: https://www.biotech-asia.org/?p=8075

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