Evaluation of Wound Healing Activity of Ficus bengalensis Shoot Tips Extract

K. Ravishankar* and A. Udayasree

Sri Sai Aditya Institute of Pharmaceutical Sciences & Research, ADB Road, Surampalem, East Godavari District, Andhra Pradesh, India.

ABSTRACT: The objective of present study is to establish the wound healing activity of Ethanolic shoot tip extract of Ficus bengalensis (Family: Moraceae). Excision model was performed to evaluate the wound healing activity in Rabbits .In excision model percentage wound contraction and period of epithelialization was determined for the extract. Povidone iodine ointment was used as Reference standard drug. From the observation of excision model, Ethanolic extract of Ficus bengalensis (400mg/kg) was found to have greater wound healing activity in terms of percentage wound contraction and period of epithelialization than that of other groups. In conclusion, our findings suggest that Ethanolic extract of Ficus bengalensis possesses better wound healing ability and may be due to the presence of phytochemicals like glycosides, tannins, flavanoids, saponins present in plant extract.

KEYWORDS: Ficus bengalensis; Excision wound; Povidone iodine

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