Measurement of Glucose Concentration Using Amplitude Modulated Ultrasound With Infrared Technique in Intralipid Phantoms and Human Whole Blood Mixed Intralipid Phantoms Of Healthy and Diabetic Subjects

Anuj Srivastava, Md Koushik Chowdhury, Shiru Sharma and Neeraj Sharma

School of Biomedical Engineering, Indian Institute of Technology (Banaras Hindu University), Varanasi, Uttar Pradesh - 221005, India

ABSTRACT: The present paper describes the results of experimentation, carried out on intralipid phantoms and human whole blood mixed intralipid phantom samples to measure various concentration of glucose. In this technique, the amplitude modulated ultrasonic waves were applied to excite the samples. As a result, different constituent molecules oscillate at their specific response frequency depending upon their physical and chemical properties. These typical signature specific oscillations are detected using infrared techniques. The output response signal is in the form of modulated light signal. It carries information about the concentration of the different constituents. This resultant output signal data is collected using infrared detector. The signal acquiring algorithm detects the glucose specific signature signals to extract the information about the glucose concentration level in different types of human whole blood mixed intralipid phantoms. Hence, this method provides a new technique for the design of amplitude-modulated ultrasound & infrared technique based noninvasive glucometer.

KEYWORDS: Intralipid phantom; Human whole blood; Noninvasive; Amplitude modulated ultrasound

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