Oxidative Stress and Other Biochemical Parameters in Hypertension of Elderly Females

Drutpal Singh Baghel¹*, P. C. Kol² and Bhaskar Reddy³

¹Department of Biochemistry, S. S. Medical College, Rewa - 486 001, India. ²Department of Pathology, S. S. Medical College, Rewa - 486 001, India. ³Department of Anatomy, S. S. Medical College, Rewa - 486 001, India.

ABSTRACT: Hypertension is more common in men than in women before menopause. After menopause, hypertension is more prevalence in women. Hypertension in pre menopausal women is associated with a higher resting heart rate and cardiac index and a lower peripheral resistance than in men with similar levels of arterial pressure. After menopause, no difference in hemodynamic can be found between men and women. This study done on female hypertensive patients admitted in G. M. and S. G. M. Hospital, S. S. Medical College, Rewa (M. P.), India. The age range was taken from 35 to 80 years. Obtained data analyzed statistically by using student 't' test. Present study concludes that hypertension is associated with increased serum potassium, glucose, plasma malondialdehyde and decreased serum sodium, protein and superoxide dismutase.

KEYWORDS: Hypertension; oxidative stress

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