Comparing the Risk Factors of Atherosclerosis in Patients Suffering from X Syndrome and Comparing it against the Normal Population

Reza Arefizadeh , Adel Johari Moghadam and Ahmad Davoodiyan

Department of Cardiology, AJA University of Medical Sciences, Tehran Iran.

Corresponding Author E-mail : ahmaddavoodiyan@gmail.com

DOI : http://dx.doi.org/10.13005/bbra/2301

ABSTRACT: X syndrome is a cardiovascular disease during which the patient suffers from chest cage pains. There is currently no certain method to treat this disease. The treatments which are usually applied now use nitrogen compounds, calcium channel blockers, heart afterload reducers and beta blockers. However, these strategies have failed to have a significant influence on improving and treating this disease. Factors of atherosclerosis and control of these factors can have a significant impact on the treatment of syndrome X. However, determining the share and influence of each factor, their measurement and comparing them against normal population is quite necessary. This research conducted for the first time studies the effect of atherosclerosis factors such as hyperlipidemia, diabetes, high blood pressure, obesity, smoking cigarettes, long stress and family record of cardiovascular diseases among those suffering from X syndrome separately and, finally, we compare these factors with normal population. Having resorted to the heart unit of Tehran’s Dey Hospital, as many as 4000 files corresponding to the patients who had undergone angiography there were studied. As many as 160 files of patients suffering from X syndrome were obtained and the information corresponding to each variable was extracted and registered in the special form prepared for this purpose. The EF of each atherosclerosis factor was analyzed compared to its negative counterpart. Then each factor was measured and compared against the normal population using SPSS and Pearson chi square test. EF was considered as a variable representing the intensity of disease and the level of functioning disruption. Then, other risk factors were compared against it. Gender, diabetes, hyperlipidemia, smoking, obesity and high blood pressure had no significant correlation with the level of EF of patients. However, there was a statistically significant correlation between long-term stress and EF and the level of EF in the group with positive long-term stress was significantly less than what was observed in negative stress group. Considering the ODDS Ratio calculated, obesity with an ODDS Ratio of 6.711 has the greatest correlation with X syndrome and it has the highest preference for future interventional studies on the effect of treating risk factors on reducing the symptoms of those patients suffering from X syndrome. obesity possesses the greatest preference for interventional studies in order to study the influence of treating risk factors of atherosclerosis on reducing the symptoms and enhancing the recovery of disease in patients suffering from heart X syndrome.

KEYWORDS: X Syndrome; Cardiovascular Disease; Obesity; Atherosclerosis Factors; Heart Disease

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