Albumin Utilization Review to Evaluate the Efficacy and Cost, Perform as A Qualitative Study in Special Wards in Shaheed Rajaei Cardiovascular, Medical and Research Center

Bahram Fariborz Farsad¹, Naser Hadavand^1*and Sahar Masumi²

¹Pharm.D, BCPS, Assistant Professor, Rajaie Cardiovascular Medical and Research Center, Iran University of Medical sciences, Tehran, Iran.

²Pharmaceutical, Department of Clinical Pharmacy , Faculty of Pharmacy , Islamic Azad University , Pharmaceutical Sciences Branch , Tehran , Iran.

Corresponding Author E-mail: Hadavandn@yahoo.com

DOI : http://dx.doi.org/10.13005/bbra/2290

ABSTRACT: Drug utilization studies may be one of the major design of optimizing the cost-effectiveness of treatment regimens and drugs that used to compare the costs and effects of alternative therapies. Human albumin (HA) is widely used for hypoalbuminemia and other diseases from deficiency of blood and liver factors. HA cost in the clinical setting is still controversial And Since use of albumin an established second line therapy process which is to be used in supportive drug for patients .on this study Trying to find first albumin protocol therapy cost was evaluated Then appropriate practice to be Alternate. A prospective, cross-sectional research was performed in “Shaheed Rajaei” Cardiovascular, Medical and Research Center during a 6-month continuous interval, in which, 300 patients have been evaluated  .The study included patients who on a daily basis take albumin from the central pharmacy of  Shaheed  Rajaei hospital  attaints time of receipt drug until discharge from hospital or termination of treatment were studied continuously. Demographic data including dose, intervals and durations have been registered, and then compared with international guidelines such as Data analyses have been done by SPSS 16 software. The results of this study indicated that among 300 in-patients who had prescribed albumin prescription assumed inappropriate for 281 patients (93.7%), The most common reason was incorrect indication of prescription without checking serum albumin level (56.39%) .base on this study the most reasons of albumin use were ascites and edema (57.9%),during the course of CABG(27.5%),hypoalbuminemia and hypoproteinemia(33.3%),acute nephritis(17.6%),hemodialysis(19.6%). also rate of infusion error was (16.5 %)and error related to dosages of order was ( 23.8 %).according to guidelines dosage of adminstration must be base on weight and serum albumin level that not be considred in intensive wards. According to data from this study suggests that You can see the protocol therapy based on the patient's needs  Albumin consumption to reduce the cost of treatment and  The lack of effectiveness of the drug, especially compared to other alternative medicines reduced.

KEYWORDS: Albumin Utilization; Efficacy; Cost

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