Antibiotic Resistance Pattern of Bacteria Isolated from Nosocomial Infection in Internal Surgery and Neurosurgery Intensive Care Unit (NICU) at a Tertiary Care Hospital in Tehran, Iran

Mohammad Javad Hosseini and Reza Sadripour

Molecular Biology Research Center, BaqiyatallahUniversity of Medical Sciences, Tehran, Iran.

DOI : http://dx.doi.org/10.13005/bbra/2547

ABSTRACT: Today, many studies doneregarding the antibiotic resistance showthose patients in intensive care units (ICUs) are more likely to develop drug resistant pathogens.Pathogens are the major cause of nosocomial infections in intensive care units. Knowledge of antibiotic resistance of pathogens in the hospital is very important for treatment. The recent study aims at identifying drug resistant pathogens and antibiotic resistance pattern in the intensive care units of a tertiary care hospital in Tehran. In other words, the main purpose of the recent study is understanding the degree to which the resistant bacteria, which cause nosocomial infections is spreading in the ICUs of a tertiary care hospital and to determine the antibiotic- resistance pattern of these bacteria in the ICUs of that hospital. The recent research is a retrospective and cross-sectional study that has been conducted on the files of all patients who were hospitalized in ICUs, internal surgery, and neurosurgery sections of Baqiyatallah Hospital in Tehran in a five-year period (March 2009 to February 2015) and who were diagnosed with nosocomial infection caused by resistant bacteria. According to the results of this research, most of the separated bacteria were: Acinetobacterbaumannii 39.45%, Pseudomonas aeruginosa 20.69% and the most common location for infection was respiratory tract (67.11%). Also the most common pathogen was Acinetobacterbaumannii which is resistant to most antibiotics.

KEYWORDS: Antibiotic resistance; ICU; nosocomial infection

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