Antidiabetic Effect of Burdock Tuber (Arctiumlappa L.) Extract on Aloxan Diabetic

Dehghani Naeimeh¹, Daneshpazhouh Hamed¹, Asmariansheyda^2*, Shafiei Jahromi Nazanin³, Poorgholami Farzad⁴

¹Department of Biology,Payame Noor University ,19395-4697 ,Tehran, I. R. of Iran ²Department of Basic Science, Faculty of Veterinary Medicin, Kazerun Branch, Islamic Azad University, Kazerun, Iran. ³Department of Nursing, Islamic Azad University, Firuzabad Branch, Firuzabad, Iran. ⁴Reaserch center for non-Communicable Diseases, Jahrom University of Medical Sciences, Jahrom, Iran.  

ABSTRACT: Diabet is one of the most disorders in endocrine part of pancreas. use some plants whit therapeutic effect such as lapa major is a route for remedy in diabet . this study was done to virify effect of root extract of lapa major. In this investigation 36 male vistrar rat were divided into 6 group randomly. Except for group 1, in all group diabet was induced .group 2 received insulin and in group 4,5 and 6 extract was administration in dose of 100, 200 and 300 mg/kg. blood samples were collected on day 7, 14 , and 21 .result were analyzed by anova test . results indicated that the level of blood glucose were increased after induced of diabet . the level of blood glucose in group which received insulin and in all diabetic groups in day 21 decresed signhficantly . in the other groups (4, 5) the level of glucose decreased , but not significantly . insupoosed that, because of low number of cases or low number of days that extract was administration.

KEYWORDS: Antidiabetic; Arctiumlappa L.; ethanolic extract

[ HTML Full Text]