Volume 15, number 3
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Biodegradable Polycaprolactone Nanoparticles Based Drug Delivery Systems: A Short Review

Ranjith Ramanujam1, Balraj Sundaram1, Ganesh Janarthanan1, Elamparithi Devendran2, Moorthy Venkadasalam2 and M.C. John Milton1

1Research Department of Advanced Zoology and Biotechnology, Loyola College, Chennai, Tamil Nadu, India.

2Department of Biotechnology, Annai College of Arts and Science, Kumbakonam, Tamil Nadu, India.

Corresponding Author E-mail: biotechres17@gmail.com

DOI : http://dx.doi.org/10.13005/bbra/2676

ABSTRACT: Nanoparticles based drug delivery systems showing greater potential in various biomedical applications to deliver the drugs/bioactive molecules in controlled manner to the targeted site. Polycaprolactone, biodegradable polyester, owing its tailorable properties, various forms of polycaprolactone are used as drug carrier for a range of biomedical applications. Nanoprecipitation is a simple method to prepare the polycaprolactone nanoparticles to improve the bioavailability and therapeutic potential of various drugs/bioactive molecules. This short review focused on the preparation of polycaprolactone nanoparticles using nanoprecipitation method, nanoparticles-drug formulations and its use in various drug delivery applications.

KEYWORDS: Controlled Drug Release; Drug Delivery; Nanoprecipitation; Polycaprolactone Nanoparticles

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Ramanujamv R, Sundaram B, Janarthanan G, Devendran E, Venkadasalam M, Milton M. C. J. Biodegradable Polycaprolactone Nanoparticles Based Drug Delivery Systems: A Short Review. Biosci Biotech Res Asia 2018;15(3).
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Ramanujamv R, Sundaram B, Janarthanan G, Devendran E, Venkadasalam M, Milton M. C. J. Biodegradable Polycaprolactone Nanoparticles Based Drug Delivery Systems: A Short Review. Biosci Biotech Res Asia 2018;15(3). Available from: https://www.biotech-asia.org/?p=31040

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