Volume 3, number 2(a)

Colon - Targeted Drug Delivery System: A Review

Neeraj Sharma, P.K. Sharma, Nisha Mary Joseph and Mayank Bansal

KIET School of Pharmacy, Gaziabad (India)

ABSTRACT: Inflammatory2 bowel diseases including irritable bowl syndrome, ulcerative colitis and crohn’s disease are considered serious colonic disorder. Ulcerative colotis, if not treated, leads to colon cancer. More than 66,000 cases of colon cancer are reported to occur every year in India. Cancer of large intestine accounts for about 15% of cancer death in India. Oral delivery has become a widely accepted route of administration of therapeutic drug, the gastrointestinal3 tract present several formidable barrier to drug delivery. Colonic drug delivery is also found useful for improving systemic absorption of drug like nitrendipine, metoprolol, theophylline, isosorbide Mônonitrate.

KEYWORDS: Bowel Diseases, Gastrointestinal Tract, Isosorbide Mônnitrate, Metoprolol,  Nitrendipine, Theophylline, Ulcerative Colitis

Copy the following to cite this article:

Sharma N, Sharma P. K, Joseph N. M, Bansal M. Colon - Targeted Drug Delivery System: A Review. Biosci Biotech Res Asia 2006;3(2a).
Copy the following to cite this URL:

Sharma N, Sharma P. K, Joseph N. M, Bansal M. Colon - Targeted Drug Delivery System: A Review. Biosci Biotech Res Asia 2006;3(2a). Available from: https://bit.ly/3gk3lpu

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