Recent Upgradation in Bioanalytical Studies

Rakesh Shelke^* and Dinesh Rishipathak

Department of Pharmaceutical Chemistry, Mumbai Education Trust’s, Institute of Pharmacy, BKCs Adgaon, Nashik, Maharashtra, (M.S.), India-422003

Corresponding Author E-mail: rshelke07@gmail.com

DOI : http://dx.doi.org/10.13005/bbra/2972

ABSTRACT:

Analytical methodologies are critical throughout the medicine development process, including marketing and post-marketing studies. The advancement of bio-analytical techniques has resulted in a dynamic field with many exciting potentials for further advancement in the future. Bio-analysis is commonly utilised in the pharmaceutical drug development of drug's and its metabolites' quantitative levels. The goal is to undertake pharmacokinetic and pharmacodynamic studies, as well as kinetics, toxicokinetics, bioequivalence, and exposure studies. Bioanalytical research employs a variety of bioanalytical techniques, including new instrumental techniques, separation techniques, and ligand-Indused test. This study emphasizes the importance of bio-analytical techniques and hyphenated devices in evaluating drug bio-analysis and the role of several current bio-analytical techniques such as LC-Mass, HPLC-PDA, UPLC-Mass spectroscopy, HPTLC, LC-Tandem, AAS, ICP-Mass.etc., and their recent modernization in drug analytical and bio-analysis investigations

KEYWORDS: Analytical techniques; Analytical testing; Bioanalysis; Bioanalytical methods

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