Metered Dose Inhalers (MDI’S) for High-Performance Pulmonary Drug Delivery in Assistance to Nanotechnology

Manali Harshal Barve^1*, Priti Kiran Shardul¹, Satish Sundarrao Munne¹ , Atul R Bendale¹ , Vaishali Naphade² , Vasim T. Pathan¹ and Laxmikant B. Borse¹

¹Sandip Institute of Pharmaceutical Sciences, Mahiravani, Nashik-422213, MS, India.

²School of Pharmaceutical Sciences, Sandip University, Nashik 422213, MS, India.

Corresponding Author E-mail: manalibarve4@gmail.com

DOI : http://dx.doi.org/10.13005/bbra/3100

ABSTRACT: Respiratory infections pose a severe danger to public health's morbidity and death on a global scale. Delivery via the lungs can be accomplished using several drug delivery tools, including nebulizers, MDI’s and dry powder inhalers. Metered dosage inhalers are the most intriguing and the clinician's first preference out of all of them. This review emphasized based on metered dose inhalers for the delivery of pulmonary drugs. This study focuses on the provision of various therapies employing lipid nanocarriers, polymeric nanoparticles dendrimers & micelles, among others, using metered dose inhalers, liposomes, solid lipid nanostructures, nanostructured lipid carriers, and other topics were thoroughly explored. The market scenario for different MDI’s as well as information on digital metered dose inhalers is also covered in this review.

KEYWORDS: Cancer; Drug Delivery; Metered Dose Inhalers; Nanocarriers; Pulmonary Delivery

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