Characterization of Antheraea assamensis Cocoon Proteins as a Potential Candidate Against Urinary Tract Infection

Raunak Raj Singh¹ , Manash Pratim Sarma¹ , Mrinmoy Basak² and Ritismita Devi^3*

¹Department of Biotechnology, Faculty of Science, Assam down town University, Assam, India.

²Faculty of Pharmaceutical Sciences, Assam down town University, Assam, India.

³Department of Biochemistry, Faculty of Science, Assam down town University

Corresponding Author E-mail:ritismitadevi@gmail.com

DOI : http://dx.doi.org/10.13005/bbra/3124

ABSTRACT: Silk is a biomaterial which is a fibrous protein with remarkable mechanical properties produced in fibre formed by silkworms and spiders. Apart from being a fine biomaterial, it has also been used since past few centuries as sutures in medical surgeries due to its advantages in healing properties and antimicrobial activity to avoid infection. Silk as a material has also been successful in various modern medical areas.¹  Here the researchers attempt to study the antimicrobial properties of silk proteins and their potential utility as medicinal agents against the bacteria of the urinary tract infections. This study was done to analyse the affect of muga silk based protein sericin and fibroin on the pathogenic bacteria causing UTI and its role in antibiotic sensitivity.  It was found that there was a potential in  both the silk proteins (Sericin and fibroin) in its anti-microbial effects against the UTI causing bacteria and had formidable results when treated against them.

KEYWORDS: Antherae aassamensis; Fibroin; Sericin; Silk; UTI

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