Volume 5, number 1
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Spectrofluorimetric estimation of Rosiglitazone in tablet dosage form

Chungath Thomas Telny1*, J. bagyalakshmi 2 and T. k. ravi 2

1*Department of Pharmaceutical Analysis, St James College of Pharmaceutical Sciences, River Bank,Chalakuddy-680 307India.

2Department of Pharmaceutical Analysis, Sri Ramakrishna Institute of Paramedical Science, Coimbatore- 641044 India.

Corresponding Author E-mail: teenujoe@gmail.com

ABSTRACT: A simple and highly sensitive spectrofluorimetric method was developed for the estimation of Rosiglitazone in tablet dosage form. The native fluorescence of the drug in methanol was measured at an excitation wavelength of 297nm and emission wavelength of 311nm. Rosiglitazone was estimated in nanograms and its linearity was found to be 1-5ng/ml. The method was found to be rapid, precise and accurate which can be applied for the routine estimation of rosiglitazone in tablet dosage forms.

KEYWORDS: Fluorescence; rosiglitazone; oral antidiabetic agent and tablets

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Telny C. T, bagyalakshmi J, ravi T. K. Spectrofluorimetric Estimation of. Biosci Biotechnol Res Asia 2008;5(1)
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Telny C. T, bagyalakshmi J, ravi T. K. Spectrofluorimetric Estimation of. Biosci Biotechnol Res Asia 2008;5(1) Available from: https://www.biotech-asia.org/?p=7026

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