Volume 5, number 1
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UV-Spectrophotometric Determination of Alfuzosin Hydrochloride in Bulk and Tablets

M. Sugumaran*, P. Suresh and T. Vetrichelvan

Adhiparasakthi College of Pharmacy, Melmaruvathur - 603 319 India.

Corresponding Author E-mail: murugesansugumaran@yahoo.com

ABSTRACT: A simple, rapid, sensitive and accurate UV- spectrophotometric method has been developed for estimation of alfuzosin hydrochloride from pharmaceutical formulations. In 0.1M NaOH, alfuzosin hydrochloride showed absorbance maxima at 350 nm. Linearity was observed in the concentration range of 10-30 μg/ml (r2=0.999914). The amount of drug estimated from the formulation was found to be in the good agreement with label claim. The recovery studies were carried out at three different levels i.e. at 50%, 70% and 90%. The method was validated statistically.

KEYWORDS:

UV- spectrophotometric method; Alfuzosin hydrochloride

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Sugumaran M, Suresh P, Vetrichelvan T. Adhiparasakthi College of Pharmacy, Melmaruvathur - 603 319 (India). Biosci Biotechnol Res Asia 2008;5(1)
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Sugumaran M, Suresh P, Vetrichelvan T. Adhiparasakthi College of Pharmacy, Melmaruvathur - 603 319 (India). Biosci Biotechnol Res Asia 2008;5(1) Available from: https://www.biotech-asia.org/?p=7065

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