Volume 5, number 2
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Influence of Smoking on Activity of Salivary A-Amylase

R. Sariri*, R. H. Sajedi, H. Ghafoori and A. Varasteh

Department of Biochemistry, The University of Guilan, Rasht (Iran).

ABSTRACT: Tobacco smoke is involved in the pathogenesis of several diseases regarding different body systems. Saliva is the first body fluid to confront inhaled cigarette smoke which is injurious to the oral cavity and is associated with several oral diseases and cancer.The aim of our study was to evaluate the influence of smoking on the activity of a-amylase, in the saliva of healthy smoker individuals. a-amylase was measured in the supernatant of centrifuged saliva of 25 volunteers smokers, before and just after smoking a single cigarette using the standard chemical methodsThe enzymatic activity showed a significant inhibition following a single cigarette. Reduction in the enzymatic activity of saliva is most probably due to the interaction between smoke aldehydes and –SH groups of the enzyme molecules Based on the results obtained in the present study, it could be emphasized that smoking of just one cigarette is sufficient to alter the salivary a- mylase enzymatic activities.

KEYWORDS: Salivery enzymes; a-amylase; cigarrete smoking

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Sariri R, Sajedi R. H, Ghafoori H, Varasteh A. Influence of Smoking on Activity of Salivary A-Amylase. Biosci Biotechnol Res Asia 2008;5(2)
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Sariri R, Sajedi R. H, Ghafoori H, Varasteh A. Influence of Smoking on Activity of Salivary A-Amylase. Biosci Biotechnol Res Asia 2008;5(2). Available from: https://www.biotech-asia.org/?p=7199

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