Volume 7, number 2
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Experimental Evaluation Of Albizia Lebbeck Benth. Stem Bark for Wound Healing Activity in Mice

Nilesh Gupta and U. K. Jain*

Bhopal Institute of Technology and Science, Pharmacy Bhojpur Road, Bangrasia, Bhopal - 462 045 India.

Corresponding Author E-mail:ukjain65@gmail.com

ABSTRACT: The present study was aimed to evaluate the wound healing activity of extract of bark part of Albizia lebbeck. It is well-known plant in Indian traditional medicines. On the basis of traditional use and literature references, this plant was selected for wound healing potential. The methanolic extract of bark parts of Albizia lebbeck was examined for wound healing activity in the form of ointment in three types of wound models on mice: the excision, the incision and dead space wound model. The extract ointments showed considerable response in all the above said wound models as comparable to those of a standard drug Betadine ointment in terms of wound contracting ability, wound closure time, tensile strength and dry granuloma weight. Histological analysis was also consistent with the proposal that Albizia lebbeck bark extract exhibits significant wound healing potential.

KEYWORDS: Albizia lebbeck; Wound healing activity; Betadine; Methanolic extract

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Gupta N Jain U. K. Experimental Evaluation Of Albizia Lebbeck Benth. Stem Bark for Wound Healing Activity in Mice. Biosci Biotech Res Asia 2010;7(2)
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Gupta N Jain U. K. Experimental Evaluation Of Albizia Lebbeck Benth. Stem Bark for Wound Healing Activity in Mice. Biosci Biotech Res Asia 2010;7(2). Available from:http://www.biotech- asia.org/?p=9275

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