Study on Radical Scavenging Activity and Analysis of Bioactive Compounds in Selected Indian Medicinal Plants  

Seema kumari²*, M. Rama Rao¹, I. Bhaskar Reddy¹ and V. Rama Rao²*

¹Department of Biochemistry, College of Science, Gitam University, Rushikonda, Visakhapatnam - 45 India. *

²MVR.P.G. College, Visakhapatnam - 45 India.

Corresponding Author E-mail: seemakumarisingh@gmail.com

ABSTRACT: Antioxidant therapy promises effective role in treatment of diseases caused due to free radicals. The present study is to examine the antioxidant potential of selected medicinal plants namely Nardostachys jatamansi, Swertia chirayita, Glycyrrhiza glabra, Zingiber officinale, Carum carvi, Trachyspermum ammi, Madhucana indica ,Berberries aristata, Fenniculum vulgare, Myristica fragans. Ethanolic extract were used for analysis. B.aristata showed highest radical scavenging effect on the stable DPPH. radical with IC50 (95.9%) followed by M. fragrans with IC50 (91.8%) which is high in comparison with synthetic antioxidant BHT (74.8%). Superoxide radical scavenging activity, hydroxyl radical scavenging activities, Total antioxidant power, invitro lipid peroxidation were evaluated using concentration range of 1gm,5gm,10gm,15gm,20gm/100ml .Antioxidant activity is reported due to presence of bioactive compounds hence analysed presence of phenols, flavonoids, alkaloids.

KEYWORDS: DPPH radicals; in vitro lipid peroxidation; BHT; Phenols

[ HTML Full Text]