Volume 7, number 1
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Study of the Chromosomal Changes in the Cervical Carcinoma

Parvinder Kour, Mohan Lal, rakesh Panjaliya, Vikas Dogra and Subash Gupta

Human genetic research cum counseling centre, department of zoology, university of Jammu, Jammu - 180 006 India.

Corresponding Author E-mail:parimanu@gmail.com

ABSTRACT: The present study, which was conducted in the Department of Gynecology and Obstetrics SMGS Hospital, Government Medical College, Jammu and Human Genetic Research cum Counselling Centre, University of Jammu, aimed at to analyze the chromosomal changes in fifty (50) cases of the cervical carcinoma by in vivo technique. Some non cytogenetic factors like age, early marriage, high parity, cigarette smoking, race and low socio-economic status which are considered as risk factors for cervical cancer were also studied. Both the numerical and structural chromosomal changes have been recorded in majority of these growths. In most of the cases numerical aberrations (95%) out numbered the structural aberrations. The numerical aberrations include aneuploidy and hyperdiploidy. Structural aberrations include translocations and deletions.

KEYWORDS:

Cervical carcinoma; aneuploidy; aberrations; parity.

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Kour P, Lal M, Panjaliya R, Dogra V, Gupta S. Study of the Chromosomal Changes in the Cervical Carcinoma. Biosci Biotech Res Asia 2010;7(1)

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Kour P, Lal M, Panjaliya R, Dogra V, Gupta S. Study of the Chromosomal Changes in the Cervical Carcinoma. Biosci Biotech Res Asia 2010;7(1). Available from: https://www.biotech-asia.org/?p=9561

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