Volume 8, number 2
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Synthesis of 2[2/-propen-1/-one,3/-(4-hydroxy,3-azophenyl) Phenyl] Pyrroles and 2[2/-propen-1/-one-3/- (3-hydroxy Naphthyl-1-azo) Phenyl] Pyrroles

Meghasham N. Narule

Department of Chemistry, RTM Nagpur University, Nagpur - 440 033 (India).

ABSTRACT: A facile synthesis of 2[2/-propene-1-one-3-(4-hydroxy, 3/-azophenyl) pheny] pyrroles (3a-h) and 2[2/-propene-1-one-3-(4/-hydroxy naphthyl-1-azo) pheny]pyrroles (6a-c) has been achieved by 2[4/-hydroxy benz-1(propane-1-one)] pyrrole 2 and 2[3/-amino benz-1(propene-1-one) ] pyrrole 5 respectively The newly synthesized compounds structures have been supported by IR, 1H NMR, spectral data. The antibacterial and antifungal activities of the compounds have also been evaluated.

KEYWORDS: Pyrrole; azo compounds; 4-hydroxy benzaldehyde

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Narule M. N. Synthesis of 2[2/-propen-1/-one,3/-(4-hydroxy,3-azophenyl) Phenyl] Pyrroles and 2[2/-propen-1/-one-3/- (3-hydroxy Naphthyl-1-azo) Phenyl] Pyrroles. Biosci Biotech Res Asia 2011;8(2)
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Narule M. N. Synthesis of 2[2/-propen-1/-one,3/-(4-hydroxy,3-azophenyl) Phenyl] Pyrroles and 2[2/-propen-1/-one-3/- (3-hydroxy Naphthyl-1-azo) Phenyl] Pyrroles. Biosci Biotech Res Asia 2011;8(2). Available from: https://www.biotech-asia.org/?p=9626

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