Antibacterial Activities of Ipomoea Carnea Stem

Elija Khatiwora¹, Vaishali B. Adsul², Anjali D. Ruikar¹, N.R. Deshpande¹ and R.V. Kashalkar¹

¹Dr. T.R. Ingle Research Laboratory, Department of Chemistry, S.P. College, Pune - 411 030 India.

²Department of Chemistry, Y.M.College, Bharati Vidyapeeth, Pune - 38 India.

Corresponding Author E-mail:ekhatiwora@yahoo.com

ABSTRACT: Natural products are used as traditional medicines from ancient times. They are having a great importance in Ayurveda. One of the medicinal plant species is Ipomoea carnea,which belongs to convolvulaceae family and fistulosa sub-family. Many Ipomoea species having antimicrobial activities were reported in literature. The present study explored the antibacterial activities of hexane, chloroform, ethyl acetate, acetone and methanol extracts of stem of I. carnea against, gram negative bacteria Escherichia coli(ATCC10536),Klebseilla pneumoniae (ATCC33495),Proteus mirabilis (ATCC12453) and Pseudomonas aeruginosa (ATCC10662) and gram positive becteria Bacillus subtilis (ATCC11774), Staphylococcus aureus (ATCC1026) and Bacillus cereus (ATCC10876). Air shade dried powdered material was extracted using solvents of increasing polarity from non-polar (n-haxane) to polar (methanol) solvents. These extracts were tested against above seven bacterial strains in concentration 40 ?L/ml. The antibacterial activity was determined by using disc diffusion method. Streptomycin was used as a standard. Acetone and methanol extracts of I. carnea stem showed significant activity. Therefore, these extracts were selected for further investigation to determine its therapeutic potential.

KEYWORDS: Ipomoea carnea; extract; antibacterial activity; dics diffusion method; Steptomycin.

[ HTML Full Text]