Prevalence of Sickle Cell Anemia and Thalassemia among Anemic Patients of Al-Noor Specialist Hospital, Makkah, KSA

Sickle Cell Anemia, Anemic Patients and Thalassemia H. Faidah^1,2, M. Samy² and A. A Tashkandi³

¹Umm AL Qura University, Faculty of Medicine. ²Alnoor Specialist Hospital, Laboratory and Blood Bank Department ³National Guard Hospital, Emergency Department..

DOI : http://dx.doi.org/10.13005/bbra/1089

ABSTRACT: This study aimed to to determine the prevalence of Sickle cell diseases and trait and high hemoglobin (Hb) A2 b- thalassemia in the province of Makkah among patients of Al-Noor Specialist hospital, Makkah. Retrospective studying the results of 620 requested saudi patients (256 male and 364 female) suffer from Anemia for gel electrophoresis. Covering the period between 1 January 2012 to 30 December 2012 was presented. It was found a significant increase (P<0.05) in prevalence of anemia among females compared to males (1.42/1 ratio). The prevalence for Sickle cell anemia was (38.38%) which showed highly significant increase comparing with (P>0.01) ²-Thalassmia (5.32%) and Non A2 Hemoglobin (2.90%). ²-Thalassmia also, showed significant increase P<0.05) compared with Non A2 Hemoglobin. Hemoglobinopathies occurs frequently among our patients, with majority of cases having Sickle cells anaemia, and cases with heterozygous mutation (trait disease) was the predominant.

KEYWORDS: Sickle Cell Anemia; Anemic Patients; Thalassemia

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