Manuscript accepted on : 10 October 2014
Published online on: --
Molecular Modelling and Structure analysis of S-ribosyl homocysteinase from Aeromonas hydrophila
T.Yuvarani1, V. Anuradha2, N. Yogananth3, M. Syed Ali3 and R. Karthik4
1Department of Biotechnology, D.G.Vaishnav College, Arumbakkam, Chennai -600106, India 2Department of Biochemistry, Mohamed Sathak College of Arts & Science, Sholinganallur, Chennai-600119, India 3Department of Biotechnology, Mohamed Sathak College of Arts & Science, Sholinganallur, Chennai-600119, Tamilnadu, India 4Department of Marine Biotechnology, AMET University, Kanathur, Chennai - 603112.
DOI : http://dx.doi.org/10.13005/bbra/1432
ABSTRACT: In the Present study, Molecular modelling and structure analysis was performed for S-ribosyl homocysteinase from Aeromonas hydrophila. This is to determine new set of compounds that can be explored as antibiotics sensing and targeting the Quorum sensing proteins. The Probable ligands and their binding sites were also determined using ligprof server. HPS[2- Amino- 4- Mercapto- Butyric acid] was found to be the best ligand which can bind to the 3D structure of the target protein.
KEYWORDS: Aeromonas hydrophila; Quorum sensing; S-ribosyl homocysteinase; AI-2 synthase; Insilico analysis
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| Copy the following to cite this article: Yuvarani T, Anuradha V, Yogananth N, Ali M. S, Karthik R. Molecular Modelling and Structure analysis of S-ribosyl homocysteinase from Aeromonas hydrophila. Biosci Biotech Res Asia 2014;11(spl.edn.1) |
| Copy the following to cite this URL: Yuvarani T, Anuradha V, Yogananth N, Ali M. S, Karthik R. Molecular Modelling and Structure analysis of S-ribosyl homocysteinase from Aeromonas hydrophila. Biosci Biotech Res Asia 2014;11(spl.edn.1). Available from:https://www.biotech-asia.org/?p=11889 |
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