Studies on Green Synthesis, Characterization and Anti-proliferative Potential of Silver Nano Particle using Dodonaea viscosa and Capparis decidua

T. Giridharan¹, Chandran Masi¹*, S. Sindhu² and P. Arumugam²

¹Department of Biotechnology, Vel tech High tech Dr. RR Dr. SR Engineering College, Avadi, Chennai - 600 062, India. ² Armats Biotek Pvt Ltd, Guindy, Chennai - 600 032, India.

ABSTRACT: The aim of this study is to evaluate the anti-proliferative activity of silver nanoparticles synthesized using D.viscosa and C.decidua. The leaves of the plants were used for optimization of silver nanoparticles by varying the time exposure of the reaction mixture to sunlight (5, 10, 15 minutes). The anti-oxidant potential of samples was studied by different assays. Also, the synthesized nanoparticles were characterized by UV, SEM, XRD and FTIR techniques. The results suggest that nanoparticles synthesis was significant at exposure time of 5 and 10 minutes. The synthesized particles were confirmed by UV spectroscopy which showed characteristic peak at 421nm for both the samples. The synthesized nanoparticles were found to be in the size range of 60-90nm and possessed characteristic XRD peaks. The results of the study revealed that the synthesized silver nanoparticles possessed significant antioxidant, anti inflammatory, anti-proliferative and antimicrobial properties.

KEYWORDS: Silver nanoparticles; Anti inflammatory activity; Antimicrobial potential

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