Volume 11, number 3
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Kusumawati A, Wanahari T. A, Putri R. F, Untari T, Hartati S, Mappakaya B. A, Putro P. P. Clinical and Pathological Perspectives of Jembrana Disease Virus Infection: A Review. Biosci Biotech Res Asia 2014;11(3).
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Clinical and Pathological Perspectives of Jembrana Disease Virus Infection: A Review

Asmarani Kusumawati1,2*, Tenri Ashari Wanahari3, Rizqa Febriliany Putri3, Tri Untari4, Sri Hartati5, Basofi Ashari Mappakaya3 and Prabowo Purwono Putro1

1Departement of Reproduction, Faculty of Veterinary Medicine, Gadjah Mada University, Jalan sekip unit II, Yogyakarta, 55281 Indonesia. 2Centre of Biotechnology Study, Gadjah Mada University, Jalan teknika utara, Yogyakarta, 55281 Indonesia. 3Faculty of Medicine, Sebelas Maret University, Jalan Ir. Sutami 36 A, Surakarta, 57126 Indonesia. 4Departement of Microbiology, Faculty of Veterinary Medicine, Gadjah Mada University, Jalan sekip unit II, Yogyakarta, 55281 Indonesia. 5Department of Internal Medicine, Faculty of Veterinary Medicine, Gadjah Mada University, Jalan sekip unit II, Yogyakarta, 55281 Indonesia.

DOI : http://dx.doi.org/ http://dx.doi.org/10.13005/bbra/1509

ABSTRACT:

Jembrana disease virus (JDV) is a viral pathogen that causes Jembrana disease in Bali cattle (Bos javanicus). Jembrana disease poses the major concern in Bali cattle industry as it gives rise to significant economic detriment due to mortality of cattle. During the first outbreaks, mortality of approximately 60000 cattles in a year was observed due to JDV infection. The pathology of JDV is unusual for a lentivirus infection as it is associated with an clinically acute, often lethal disease syndrome, and a short incubation period in Bali cattle. Studies of Bali cattle experimentally infected with JDV have provided insights into haematological change, cytopathological response, and immune response in naturally occurring infection. The localization of JDV in various tissues or organs were also had been reported. This review discusses the progression of clinical symptoms and the pathological changes during the development of Jembrana disease.

KEYWORDS:

Jembrana disease; virus distribution; Cytophatology; immunopathology, clinical progression.

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Kusumawati A, Wanahari T. A, Putri R. F, Untari T, Hartati S, Mappakaya B. A, Putro P. P. Clinical and Pathological Perspectives of Jembrana Disease Virus Infection: A Review. Biosci Biotech Res Asia 2014;11(3).
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Kusumawati A, Wanahari T. A, Putri R. F, Untari T, Hartati S, Mappakaya B. A, Putro P. P. Clinical and Pathological Perspectives of Jembrana Disease Virus Infection: A Review. Biosci Biotech Res Asia 2014;11(3). Available from: https://www.biotech-asia.org/?p=10296
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