Manuscript accepted on : November 25
Published online on: 03-02-2016
Pharmacological evaluation of thiazolidinone derivatives for anti-ulcer and antibacterial activities
Basavaraj Hulkoti1*, A.D. Taranalli2, Purnima Ashok1 and A. Thirugnana sambanthan3
1Department of Pharmacology, K.L.E.S’s College of Pharmacy, Bangalore (India) 2Department of Pharmacology, K.L.E.S’s College of Pharmacy, Belgaum (India) 3Department of Pharmaceutical Chemistry, K.L.E.S’s College of Pharmacy, Bangalore (India)
ABSTRACT: The newly synthesized thiazolidinone derivatives were evaluated for anti-ulcer and antibacterial activities. The anti-ulcer activity of thiazolidinone derivatives was screened by pylorus ligation and ethanol-induced ulcer methods in the doses of 20 and 30mg/kg. All the four test compounds showed significant percentage preventive ulcer ratio when compared to standard. The antibacterial activity was screened by agar cup plate method and the test compounds have also shown significant activity against gram-positive and gram-negative organisms compared to their standards.
KEYWORDS: Anti-ulcer; anti-bacterial; thiazolidinone
Download this article as:
| Copy the following to cite this article: Hulkoti B, Taranalli A. D, Ashok P, Sambanthan A. T. Pharmacological evaluation of thiazolidinone derivatives for anti-ulcer and antibacterial activities. Biosci Biotechnol Res Asia 2007;4(2) |
| Copy the following to cite this URL: Hulkoti B, Taranalli A. D, Ashok P, Sambanthan A. T. Pharmacological evaluation of thiazolidinone derivatives for anti-ulcer and antibacterial activities. Biosci Biotechnol Res Asia 2007;4(2). Available from: https://www.biotech-asia.org/?p=6017 |
This work is licensed under a Creative Commons Attribution 4.0 International License.
