Manuscript accepted on : September 29, 2007
Published online on: 05-02-2016
Jahangeer1, D. Venkappayya2 And M. N. Abubacker3*
1P.G. and Research Department of Chemistry, Jamal Mohamed College, Tiruchirapalli - 620 020 (India) 2School of Chemical and Biotechnology, SASTRA University, Thanjavur - 613 402 (India) 3P.G. and Research Department of Botany, National College, Tiruchirapalli - 620 001 (India)
ABSTRACT: Substituted cyclic ureas and thioureas having aliphatic homocyclic and heterocyclic rings were synthesized. They were screened for their antifugal activity against Cladosporium herbarum and Fusarium oxysporum.1,3 – Bis (morpholinomethyl) – imidazolidine 2- thione (MMIT) and COCl2.MMIT showed total inhibition to C.herbarum at 250, 500 and 1000 ppm concentrations, whereas 1,3-bis (morpholinomethyl)-2-imidazolidone (MMIZ) and ZnCl2.MMIZ showed total inhibition at 1000 ppm concentration towards C.herbarum. Against Fusarium oxysporum only ZnCl2.MMIT showed total inhibition at 1000 ppm concentration. Biosorption of metals on the mycelium of F. oxysporum were decreased in the other cases tried.
KEYWORDS: 1,3-bis (morpholinomethyl) -2-imidazolidone (MMIZ), 1,3-bis (morpholinomethyl) imidazolidine – 2
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| Copy the following to cite this article: Jahangeer N, Venkappayya D, Abubacker M. N. Synthesis and antifungal activity of 1, 3-bis morpholinomethyl) - 2 - imidazolidone and 1, 3-bis (morpholinomethyl) - imidazolidine - 2-thione compounds. Biosci Biotechnol Res Asia 2007;4(2) |
| Copy the following to cite this URL: Jahangeer N, Venkappayya D, Abubacker M. N. Synthesis and antifungal activity of 1, 3-bis morpholinomethyl) - 2 - imidazolidone and 1, 3-bis (morpholinomethyl) - imidazolidine - 2-thione compounds. Biosci Biotechnol Res Asia 2007;4(2). Available from: https://www.biotech-asia.org/?p=6298 |
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